Previous studies demonstrated enhanced fetal adrenal cortisol biosynthesis following exposure to long-term hypoxia (LTH). The studies presented here were designed to determine the mechanism(s) regulating this important adaptive endocrine response....
Blood flow mediated by the vascular endothelium plays an important role in removing heat from the skin. Asians who have thrifty genes have impaired endothelial function (EF) due to the westernized high fat (HF) dietary lifestyle....
Osteoporosis is a disease characterized by decreased bone mass and microarchitectural deterioration of bone. Bone loss occurs when the increased bone resorption that occurs with age is not compensated by a corresponding increase in bone formation....
Eating disorders are notoriously difficult and costly to treat, with only 40% of individuals with an eating disorder making a full recovery. Individually Tailored Service Allocation provides a dynamic treatment model defined by empirically accepted...
This dissertation was a secondary analysis of data gathered from 114 couples who had one spouse with type 2 diabetes. Diabetes management was the outcome variable. The predictor variables in this analysis included the couples’ causal attribution,...
Alterations in brain metals homeostasis and particularly brain iron overload have been postulated to play a role in Alzheimer’s disease, contributing to oxidative stress and neuronal injury; however, the source of this iron is not clear and may...
Adipose tissue secretes the adipokine, adiponectin (ADPN), which is insulinsensitizing, anti-inflammatory, and anti-atherogenic. Exercise training improves insulin sensitivity and lowers the risk of cardiovascular complications. As some of the...
Child Abuse -- Investigation -- United States; Law Enforcement; Social Case Work; Child Welfare -- United States; Social Case Work with Children -- United States
Child welfare social workers (CPS) and law enforcement professionals are the sole professional groups in California assigned the task of investigating child physical and sexual abuse allegations. Both professional groups report that...
Introduction: In the field of implant dentistry, cone beam computed tomography can give clinicians valuable information regarding anatomic structures, bone quantity and quality. If the mandibular nerve is encroached during surgery, severe morbidity...
Central Nervous System -- Growth and Development; Embryonic Development; Kidneys -- Growth and Development; Eye -- Growth and Development; Extremities -- Growth and Development
Lmx1b, a LIM homeodomain transcription factor is necessary for limb, kidney, eye, and central nervous system development. Lmx1b knockout (KO) mice display; abnormal limb dorsalization with distal ventral-ventral limbs, nephropathy, ocular...
In this study, the predictors of marital satisfaction and intimacy were examined within an African context that is characterized by a fast growing economy, migrant population, urbanization and industrialization. Specifically, this study examined...
DNA -- Synthesis; DNA -- Biosynthesis; Glycoproteins; DNA Polymerases;
Discrimination by DNA polymerases controls the fidelity of DNA replication, and reduced fidelity results in mutations essential in the etiology of cancer. Polymerase discrimination operates at both dNTP insertion and subsequent elongation steps,...
A traumatic life event such as the death of a child can be very devastating and confusing for many couples and people tend to respond in different ways to such trauma due to different factors such as gender differences. Research studies have...
