Adipose tissue secretes the adipokine, adiponectin (ADPN), which is insulinsensitizing, anti-inflammatory, and anti-atherogenic. Exercise training improves insulin sensitivity and lowers the risk of cardiovascular complications. As some of the...
The autocrine-paracrine effects of IGF2 are important in the growth and differentiation of normal breast. In breast cancer (BC), IGF2 is initially stimulated by estrogen, progesterone and prolactin to regulate proliferation and cancer progression....
The purpose of this study was to establish a foundation for developing an evidence-based assessment guideline to be used by nursing and medical personnel when evaluating a firefighter’s ability to return to work after a lower extremity injury....
Eating disorders are notoriously difficult and costly to treat, with only 40% of individuals with an eating disorder making a full recovery. Individually Tailored Service Allocation provides a dynamic treatment model defined by empirically accepted...
This dissertation was a secondary analysis of data gathered from 114 couples who had one spouse with type 2 diabetes. Diabetes management was the outcome variable. The predictor variables in this analysis included the couples’ causal attribution,...
Background: Studies have shown a decline in certain cognitive abilities in individuals diagnosed with heart disease of any type or etiology. This decline is observed as the disease progresses (Muller, Grobbee, Aleman, Bots & van der Schouw, 2006;...
Previous studies demonstrated enhanced fetal adrenal cortisol biosynthesis following exposure to long-term hypoxia (LTH). The studies presented here were designed to determine the mechanism(s) regulating this important adaptive endocrine response....
Alterations in brain metals homeostasis and particularly brain iron overload have been postulated to play a role in Alzheimer’s disease, contributing to oxidative stress and neuronal injury; however, the source of this iron is not clear and may...
Osteoporosis is a disease characterized by decreased bone mass and microarchitectural deterioration of bone. Bone loss occurs when the increased bone resorption that occurs with age is not compensated by a corresponding increase in bone formation....
Blood flow mediated by the vascular endothelium plays an important role in removing heat from the skin. Asians who have thrifty genes have impaired endothelial function (EF) due to the westernized high fat (HF) dietary lifestyle....
Heart disease remains the leading cause of death worldwide. As a result of studies done by Barker and associates, our awareness of the significance of stress during gestation as a risk factor for heart diseases has expanded. We now know that events...
Perihematomal edema causes major neurologic deterioration following
intracerebral hemorrhage (ICH), mainly resulting from the disruption of the blood-brain barrier (BBB) by multiple mediators, including inflammatory mediators and thrombin. The...
